Since 2011, the Republic of Kazakhstan has actually regularly implemented nationwide health reform programs, for which improving the high quality of cancer care is among the primary concerns. This study aimed at assessment of colon’s cancer morbidity and mortality within the period of 14 years (from 2004 to 2017). We observed a rise in the morbidity of colon cancer among the populace of Kazakhstan, which can be due to the assessment system, which started in 2011 as part of he healthcare reform program. Meanwhile, we observed a decrease in colon cancer death. The top incidence of colon cancer tumors drops in the age of 70 many years and older. Lots of Kazakhstan’s areas, including Pavlodar and East Kazakhstan have actually greater prices of colon disease morbidity.Aim of research – to investigate preliminary single center expertise in simultaneous surgical method of clients with CRCLM, their particular total Survival (OS) and Disease-Free Survival (DFS). Overall 14 patients (9 male and 5 feminine) with CRC and LM were one of them research which underwent radical multiple colorectal and liver resection.Parenchymal-sparing hepatectomy (PSH) was carried out in 13 (92,9%) clients versus anatomical resection (remaining hemihepatectomy) only in 1 (7,1%) patient. During retrospective analysis of OS and DFS we split customers in two subgroups site of primary tumor and lymph node standing. There have been no considerable postoperative problems and 30-day mortality. Median OS and DFS of patients with right side a cancerous colon was 17,3 (p=0,003) and 9,2 months (p=0,26) respectively. Median OS and DFS of patients with N+ condition was 24,3±4,8 (p=0,003) and 13 months (p=0,0004) respectively (all patients have already died, range 4 – 44 months). All customers with N0 status remain live with no indication of disease recurrence. The longest amount of DFS is around 80 months which will be however observing in 3 customers (range of observation 11 – 80 months). Multiple colon resection and PSH is hostile, excusable and cost effective surgical method in radical treatment of CRCLM which will not compromise oncological outcomes. There was no evidence of increasing of complication price. The group of clients with right sided colon cancer and those with N+ status had significant worse prognosis with poor OS and DFS.The clinical appearance of a skin tumor is of major value for medical diagnosis of both benign and cancerous neoplasias. Pedunculated development structure is strange to extremely unusual, based a tumor kind. A required necessity for pedunculated growth is a well vascularized stem. We provide a review on large and huge pedunculated tumors of epidermis to serve as yet another guidance for the clinicians to avoid diagnostic mistakes and mistreatment. The data of unusual growth design of cutaneous neoplasia is an essential not just in Bioprocessing outpatient treatment, but additionally in proper care of hospital-admitted patients.In comparison to intra-urine injuries, extra-uterine injuries will heal with a scar. A number of conventional and surgical techniques are created, aiming at increasing ugly and hypertrophic scars. The authors report to their experience with intralesional injection of the chemical hyaluronidase to boost hypertrophic scars. Hyaluronidase produces low-molecular weight fragments during digestion of high-molecular body weight hyaluronic acid. These fragments are known to stimulate angiogenesis and to stimulate mesenchymal stem cells. The manuscript presents a clinical report on number of clients with hypertrophic scars, mainly resulted from cyst resection, who have been addressed by this method.Surgical removal of tumors associated with the sacrum is associated with instability regarding the lumbar spine, pelvic band and conjunction of thereof. The procedure must be finished with fixation regarding the lumbar spine towards the pelvic ring. Traditional fixation for the lumbar spine with a pelvic ring is a long process with significant disadvantages 1) long-term bloody phase of available transpedicular fixation in the back ground of significant blood loss during tumor removal; 2) only 2 fixation points into the iliac bones, which is quite unreliable; 3) dependence on additional fixation associated with the iliac bones to each other. This study is performed to avoid disadvantages of old-fashioned transpedicular fixation after tumors for the sacrum treatment by introduction of new minimally invasive spine fixation strategy. In 9 clients (very first group) run during the Institute of Neurosurgery from 2015 to 2019 we apply Medtronic Horizon Longitude II minimally invasive system of posterior transpedicular fixation. This technique is made of 4-6 screws in the lumbar spine insmotor and bladder function ratings in both groups at the conclusion of hospital stay as contrasting to mention before operation. Both teams have similar ratings either before surgery or at the end of hospital stay. Longterm results can’t be compared because of relatively short period of surveillance of 1.9±0.17 years in the very first group comparing to 4.3±0.24 years in the control group. Posterior minimally invasive system of transpedicular fixation features benefits over standard technology of open back and pelvic ring fixation consisting in significant decrease in loss of blood and, appropriately, intraoperative risk, and reliability of fixation.Objectives – determine the influence of rib osteosynthesis regarding the occurrence of problems development and death in customers with multiple rib fractures and multiple long bone tissue cracks of reduced extremities. A prospective managed trial ended up being carried out from Summer 2015 to December 2019, and included adult patients with polytrauma, Injury Severity Score (ISS) ≥18p, several long bone fractures of reduced extremities, one of that will be the femur, and multiple rib fractures.