Bifid Triple Viable, the combination of bacillus acidophilus, bif

Bifid Triple Viable, the combination of bacillus acidophilus, bifidobacterium bifidum, and fecal streptococci, made in Shanghai Xinyi pharmacy Inc. of China, are usually used in patients with diarrhea, alteration of intestinal flora, but has not been known if it is safe and valid in treating acute pancreatitis. Objective: Goal of this study is to determine if Bifid Triple Viable, coupled with enema, is capable of preventing infectious complications Nutlin3 in severe acute pancreatitis. Methods: Fifty patients

with severe acute pancreatitis were randomized into experimental group (n = 25) and control group (n = 25). All the patients received routine treatment, including fasting, acid suppressing, antibiotics, Rhubarb and Salvia miltiorrhiza treatment. Beyond that, the patients in the treatment group will receive a daily probiotic enema with 0.5 g Bifid Triple Viable diluted in 50–100 ml normal saline until discharge. Serum amylase level, C reactive protein (CRP) value, and abdominal pain were examined, recorded and compared between two groups in order to evaluate the effectiveness

of probiotic enema in the treatment of severe acute pancreatitis. Results: Of the patients in the control group, serum amylase level returned to normal in 3.6 ± 0.7 days averagely, whereas it only took 1.9 ± 0.9 days in the experimental group. The differences were statistically significant with P < 0.05. CRP became normal in 7.8 ± 2.2 and 5.3 ± 1.4 days in control and experimental groups, respectively. Moreover, the symposium of abdominal pain disappeared

in 5.1 ± 1.6 days for the patients in PCI-32765 price the control group, while in 3.7 ± 1.1 days for those in the Alanine-glyoxylate transaminase experimental groups. All the differences were statistically significant with P < 0.05. Conclusion: On the basis of routine treatment, combination of Bifid Triple Viable and enema treatment exerted significant beneficial effects on severe acute pancreatitis. Key Word(s): 1. Bifid Triple Viable; 2. Enema; 3. Probiotics; 4. SAP; Presenting Author: CHAI SOON NGIU Additional Authors: KIAT HON LIM, DAMIEN TAN Corresponding Author: DAMIEN TAN Affiliations: Department of Gastroenterology & Hepatology, Singapore General Hospital; Department of Pathology, Singapore General Hospital; Department of Gastroenterology & Hepatology, Singapore General Hospital Objective: Endoscopic ultrasound (EUS) has become an important diagnostic tool for management of SMT. With the addition of fine needle aspiration (FNA), the accuracy of can improved up to 98%. However, EUS-FNA is not without risk and complications. We illustrate a rare complication of EUS-FNA in which a patient with pancreatic heterotopia presented with acute pancreatitis post EUS-FNA. Methods: A 57-year-old man presented with incidental finding a 2 cm submucosal tumour at the antrum during screening endoscopy.

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