In the univariate analysis, fulminant hepatic failure (odds ratio [OR] 5.714, 95% confidence interval [CI] 1.045–31.245, p = 0.027), life expectancy less than 7 days according to UNOS liver status GSK126 concentration classification (status 1 and 2a) (OR 2.97, 95% CI 0.883–8.242, p = 0.074), history of recent hemodialysis (OR 3.129, 95% CI 2.340–4.183, p = 0.043), recipient
bile duct opening number of more than 2 (OR 5.208, 95% CI 1.721–15.761, p = 0.002) were significant (p < 0.1). In the multivariate analysis, recipient bile duct opening number of more than 2 was statistically significant risk factor (OR 5.208, 95% CI 1.721–15.761, p = 0.003). Conclusion: Recipient bile duct opening number was associated with spontaneous hemobilia after LT. Further studies are required in order to clarify the role of recipient bile duct opening number in spontaneous hemobilia in LT patients. Key Word(s): 1. liver transplantation; 2. biliary complication; 3. spontaneous hemobilia; 4. risk factor Presenting Author: SOO KYUNG PARK Additional Authors: JONG HO MOON, HYUN JONG CHOI, YUN NAH LEE, TAE HOON LEE, SANG WOO CHA, YOUNG DEOK CHO, SANG HEUM PARK, SUN JOO KIM Corresponding Author: SOO-KYUNG PARK
Affiliations: Selleckchem Pexidartinib Soonchunhyang University School of Medicine, Soonchunhyang University School of Medicine, Soonchunhyang University School of Medicine, Soonchunhyang University School of Medicine, Soonchunhyang University School of Medicine, Soonchunhyang University School of Medicine, SoonChunHyang University School of Medicine, Soonchunhyang University School of Medicine Objective: Covered
self-expandable metallic stent (SEMS) may improve stent patency but have the risk of migration in comparison with uncovered stent in patients with distal malignant biliary obstruction. Intraductal placement above the papillary orifice of SEMS may MCE公司 prevent duodeno-biliary reflux after stenting. This study was performed to evaluate the efficacy of modified fully covered SEMS in patients with distal malignant biliary obstruction. Methods: Total 55 patients with distal malignant biliary obstruction and obstructive jaundice were enrolled in this study. The modified fully covered SEMS (12 mm in diameter) has center portion of smaller diameter (8 mm) and long lasso without flare in both ends. Results: Causes of biliary obstruction were 27 common bile duct cancers, 21 pancreatic cancers, 5 gallbladder cancers and 2 metastatic cancers. Intraductal stenting above the papillary orifice was performed in 83.6% (46/55). Early complication rate was 5.5% (3/55, 3 mild pancreatitis). Clinical improvement of obstructive jaundice was achieved in all enrolled patients. 11 patients with operability underwent surgical resection after stenting.