Mol Microbiol 1999,31(3):893–902.PubMedCrossRef 9. Outten FW, Outten CE, Hale J, selleck screening library O’Halloran TV: Transcriptional activation of an Escherichia coli copper efflux regulon by the chromosomal MerR homologue, cueR. J Biol Chem 2000,275(40):31024–31029.PubMedCrossRef 10. Blindauer CA, Harrison MD, Parkinson JA, Robinson AK, Cavet JS, Robinson NJ, Sadler PJ: A metallothionein containing a zinc finger within a four-metal cluster protects a bacterium from zinc toxicity. Proc Natl Acad Sci U S A 2001,98(17):9593–9598.PubMedCentralPubMedCrossRef 11. Pulliainen AT, Kauko A, Haataja S, Papageorgiou AC, Finne J: Dps/Dpr ferritin-like protein: insights into the

mechanism of iron incorporation and evidence for a central

role in cellular iron homeostasis in Streptococcus suis . Mol Microbiol 2005,57(4):1086–1100.PubMedCrossRef 12. Hantke K: Bacterial zinc uptake and regulators. Curr Opin Microbiol 2005,8(2):196–202.PubMedCrossRef MX69 datasheet 13. Moore CM, Helmann JD: Metal ion homeostasis in Bacillus subtilis . Curr Opin Microbiol 2005,8(2):188–195.PubMedCrossRef 14. Carpenter BM, Whitmire JM, Merrell DS: This is not your mother’s repressor: the complex role of fur in pathogenesis. Infect Immun 2009,77(7):2590–2601.PubMedCentralPubMedCrossRef 15. Horsburgh MJ, Ingham E, Foster SJ: In Staphylococcus aureus , Fur is an interactive regulator with PerR, contributes to virulence, and Is necessary for oxidative stress resistance through positive regulation of catalase and iron homeostasis. J Bacteriol 2001,183(2):468–475.PubMedCentralPubMedCrossRef 16. Wösten MM, Kox LF, Chamnongpol S, Soncini FC, Groisman EA: A signal transduction

system that responds to extracellular iron. Cell 2000,103(1):113–125.PubMedCrossRef 17. Gunn JS: The Salmonella PmrAB regulon: lipopolysaccharide modifications, antimicrobial peptide resistance and more. Trends Microbiol 2008,16(6):284–290.PubMedCrossRef 18. Nishino K, Hsu FF, Turk J, Cromie MJ, Wosten MM, Groisman EA: Identification of the lipopolysaccharide modifications controlled by the Salmonella PmrA/PmrB system mediating resistance to Fe(III) and Al(III). Mol Microbiol 2006,61(3):645–654.PubMedCentralPubMedCrossRef 19. Kato A, Chen HD, Latifi T, Groisman Decitabine EA: Reciprocal control between a bacterium’s regulatory system and the modification status of its lipopolysaccharide. Mol Cell 2012,47(6):897–908.PubMedCentralPubMedCrossRef 20. Ogasawara H, Shinohara S, Yamamoto K, Ishihama A: Novel regulation targets of the metal-response BasS-BasR HDAC assay two-component system of Escherichia coli . Microbiology 2012,158(Pt 6):1482–1492.PubMedCrossRef 21. Leonhartsberger S, Huber A, Lottspeich F, Bock A: The hydH/G Genes from Escherichia coli code for a zinc and lead responsive two-component regulatory system. J Mol Biol 2001,307(1):93–105.PubMedCrossRef 22.