“
“Purpose of review
The purpose of this review is to examine the appropriateness of coronary artery bypass grafting (CABG) for the patient with ischemic cardiomyopathy and congestive heart failure.
Recent findings
CABG is the gold standard therapy for patients with advanced multivessel and left main coronary artery disease. A critical analysis of the Surgical Treatment of Ischemic Heart Failure (STICH) trial confirms the benefit of CABG for patients with ischemic cardiomyopathy.
Summary
CABG can be safely applied to patients with heart failure and provides benefit for appropriately selleck selected patients.”
“OBJECTIVE:
To estimate mortality ratios for all reported pregnancy deaths in the United States, 1999-2005, and to estimate the effect of the
1999 implementation of International Classification of Diseases, Tenth Revision (ICD-10) and adoption of the U.S. Standard Certificate of Death, 2003 Revision, on the ascertainment of deaths resulting from pregnancy.
METHODS: We combined information on pregnancy deaths from the National Vital Statistics System and the Pregnancy Mortality Surveillance System to estimate maternal (during or within 42 days of pregnancy) and pregnancy-related (during or within 1 year of pregnancy) mortality ratios (deaths per 100,000 live births). Data for 1995-1997, 1999-2002, and 2003-2005 were compared in order to estimate the effects of the change to ICD-10 and the inclusion of a pregnancy checkbox on the death YM155 certificate.
RESULTS: The maternal mortality ratio increased significantly from 11.6 in 1995-1997 to 13.1 for
1999-2002 and 15.3 in 2003-2005; the pregnancy-related mortality ratio increased significantly from 12.6 to 14.7 and 18.1 during the same periods. Vital statistics identified significantly more indirect maternal deaths in Birinapant chemical structure 2002-2005 than in 1999-2002. Between 2002 and 2005, mortality ratios increased significantly among 19 states using the revised death certificate with a pregnancy checkbox; ratios did not increase in states without a checkbox.
CONCLUSION: Changes in ICD-10 and the 2003 revision of the death certificate increased ascertainment of pregnancy deaths. The changes may also have contributed to misclassification of some deaths as maternal in the vital statistics system. Combining data from both systems estimates higher pregnancy mortality ratios than from either system individually. (Obstet Gynecol 2011;118:104-10) DOI: 10.1097/AOG.0b013e31821fd49d”
“Purpose To study the effects of topical administration of 1% morphine on corneal analgesia in rabbits submitted to lamellar keratectomy and to assess the expression of matrix metalloproteinase-1, metalloproteinase-2, metalloproteinase-9 (MMPs), type IV collagen, and interleukin-10 (IL-10) during the treatment. Methods Morphine group (MG) received 50 mu L of topical 1% morphine four times daily, while the control group received saline instead.