The increased volume of EPCs and VEGF were positively correlated in group 3. Our results showed that transcatheter closure of PDA and ASD in children does not lead to increased circulating level of EPCs. Transcatheter closure of VSD may result in vascular endothelium injury as indicated by increased circulating EPC level.”
“Background:
Colonic perforation is a rare complication associated with colonoscopy. There are no population-based studies on the risk of colonic perforation in IBD inpatients.
Aim: We sought to determine the prevalence of colonic perforation during colonoscopy among IBD inpatients, and to assess its risk factors.
Materials and methods: We obtained patient data from the Nationwide Inpatient Sample and used the International mTOR inhibitor drugs Classification of Diseases, the 9th revision, clinical modification codes, to identify IBD patients who had undergone colonoscopy in 2006. The control group consisted of inpatients who had colonoscopy without IBD.
Results: Colonic perforation occurred in 344/33,732 (1%) IBD hospitalizations and in 3658/578,458 (0.6%) controls without IBD Givinostat solubility dmso (P=0.0001). The risk of colonic
perforation in the IBD group was significantly higher than the control group even after adjusting for age, gender, comorbidities and endoscopic interventions including endoscopic dilations and colonoscopic polypectomy, with adjusted odds ratio (aOR) of 1.83 (95% confidence interval [CI]: 1.40, 2.38). In HKI 272 addition, older age (aOR= 1.01, 95% CI: 1.006-1.015), female gender (aOR = 1.20; 95% CI: 1.04, 1.38), and therapeutic endoscopic dilation (aOR = 6.63; 95% CI: 3.95, 11.11) were independent risk factors for perforation. Colonoscopic biopsy, polypectomy and the presence of comorbidities did not increase the risk of perforation.
Conclusions: There appears to be a higher risk of colonoscopy-associated perforation in IBD inpatients than non-IBD controls. In addition,
older age, female patients and endoscopic dilations appeared to be associated with an increased risk for perforation. (C) 2010 European Crohn’s and Colitis Organisation. Published by Elsevier B.V. All rights reserved.”
“Objectives: The first objective of the current observational study was to assess the levels of religiosity in Greek Christian Orthodox cancer patients receiving chemotherapy. The second objective was to evaluate the associations between religiosity and quality of life (QoL), an endpoint of considerable importance in clinical cancer research and practice.
Method: One hundred eighteen adult outpatients with solid tumors, who consented to participate, were administered the Systems of Belief Inventory (SBI-15R) and the European Organisation for Research and Treatment of Cancer (EORTC QLQ-C30) questionnaire.