The rate of SSIs and the risk factors for their occurrence were calculated and compared between the two groups.
Results: Antisepsis with chlorhexidine and alcohol was
associated with a lower rate of SSIs, 10.43% versus 3.07% with povidone-iodine (p=0.08). The two groups of patients were similar in baseline characteristics. Risk factors associated with SSIs were body mass index, urgent CS, and the use of the povidone-iodine protocol.
Conclusions: Antisepsis with Chlorhexidine-based regimen was associated with a significant reduction in the rate of SSIs compared to povidone-iodine antisepsis in women undergoing elective and non-elective CS. This is of extreme clinical importance, as a change Selleckchem AZD7762 in antisepsis protocol can significantly reduce the morbidity and healthcare costs regarding cesarean sections.”
“We have used Brownian dynamics-finite
element method to examine two conformational preconditioning approaches for improving DNA stretching in a microcontraction for the purpose of direct gene analysis. The newly 3-MA order proposed “”pre-stretching”" strategy is found to significantly improve the degree of DNA extension at the exit of the contraction. On the other hand, applying an oscillating extensional field to DNA yields no preconditioning effect. Detailed analysis of the evolution of DNA extension and conformation reveals that the success of our “”pre-stretching”" strategy relies on the “”non-local”" effect that cannot be predicted using simple kinematics analysis. In other words, accurate prediction can only be obtained using detailed simulations. Comparing to
the existing preconditioning strategies, our “”pre-stretching”" method is easy to implement while still providing a very good performance. We hope that the insight gained from this study can be useful for future design of biomicrofluidic devices for DNA manipulation. (C) 2011 American Institute of Physics. [doi:10.1063/1.3655565]“
“BACKGROUND A large number of commercial antiwrinkle and antiaging compounds are available to consumers for rejuvenation of facial skin ravaged by age or solar radiation. Experimental data compound inhibitor on the histological effects of these commercial products in laboratory models are sparse.
OBJECTIVES To compare the efficacy of topical application of five commercially available antiaging compounds (retinoic acid, glycolic acid, vitamin C, estrogen, and soy) on the dorsal skin.
METHODS AND MATERIALS The effects were examined using light microscopic analysis of the epidermis in the normal nonirradiated hairless mouse. The agents were applied daily to dorsal tattooed areas for 2 weeks before histological assessment; neighboring untreated surface areas were used as control.