There is always a possibility of selection bias, and that the patients studied were a population preselected to develop adenomas while on statins. Another weakness to our study is that the type of statin

used was unknown, as the type of statin may influence tissue response. Lipophilic statins are more likely to achieve higher drug levels in nonhepatic tissues, thus being more likely to alter the biology of colorectal Inhibitors,research,lifescience,medical mucosa than hydrophilic statins (16). Strengths include a diverse patient population sample representative of the sellectchem actual growing US population. Additionally, our analysis controlled for multiple confounding data that could influence adenoma detection. In summary, we have determined that combined aspirin and statin use, along with the sole use of aspirin, does not protect against CRA and was associated

with their presence in the Hispanic population. It is unclear why combined use of aspirin and statin medications was associated with colonoscopy findings Inhibitors,research,lifescience,medical in Hispanics. Our findings may be due to environmental factors such as dietary, colonic Inhibitors,research,lifescience,medical flora, or genetic susceptibility. Overall, we have demonstrated there is an association with the presence of CRA and aspirin/statin use, and our results support further investigation of this finding in the Hispanic population. Acknowledgements Disclosure: The authors declare no conflict of interest.
Cancer is a biggest burden of modern society. This is the second most common disease after cardiovascular disorders for maximum deaths in the world (1). Carcinoma of the stomach is a second leading cause of cancer death Inhibitors,research,lifescience,medical worldwide. The incidence of gastric cancer varies in different parts of the world and among various ethnic groups. It remains the fifth most common cancer among males and

seventh most common cancer among females in India (2). However, the overall incidence of gastric cancer in India is less compared to the worldwide incidence and India falls under the low incidence normally region category for gastric cancer. Incidence of gastric cancer varies widely among the various regions within India due diverse Inhibitors,research,lifescience,medical culture and related food habits. Reports from the National Cancer Registry Batimastat Programme (NCRP) 2010, suggested that the mean age-adjusted rate (AAR) of gastric cancer among urban registries in India varied from 3.0 to 13.2, with the highest rate being recorded in Chennai registry (3-5). However, the prevalence was found to be much higher in the north eastern region of India. Currently, the north eastern state of Mizoram occupies the first position among Indian states and fifth position globally with AAR of 46.3 to 70.2 (6). The prevalence of gastric cancer is also high in the state of Manipur. Based on our Hospital Based Cancer Registry (HBCR) 2012 gastric cancer is the second most common cancer among males comprising 6.1% of all the cancers and represents 2% in females.